You certainly can disable the IPV6 without harm if your not using iv6 enabled applications in your infrastructure.
There are some instances where it is offered to disable ipv6 http://support.microsoft.com/default.aspx/kb/952842
to completely remove the ipv6 from your computer please do the following
Right Click Network Places
Select Manage Network Connections For each enabled and used NIC
Right Click – Local Area Connection – Select Properties
after doing the above procedure you might have to use the registry editor aswell to completely disable the ipv6 tunnel
To completely disable IPv6 on a Windows Server 2008-based computer yourself, follow these steps:
- Open Registry Editor.
- Locate the following registry subkey:
- In the details pane, click New, and then click DWORD (32-bit) Value.
- Type DisabledComponents, and then press ENTER.
- Double-click DisabledComponents, and then type 0xffffffff in Hexadecimal or 4294967295 in Decimal.Note The 0xffffffff value or the 4294967295 value disables all IPv6 components except for the IPv6 loopback interface.